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Ranchi

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ICMR-NIMR Field Unit: Ranchi, Jharkhand

In order to find solution to control vector borne diseases, a Field Unit (FU) was opened at Itki, Ranchi in April 2006. The primary objective of the FU was to develop an eco-friendly, cost effective and sustainable intervention technology for the control of tribal malaria and other vector borne diseases in Jharkhand state with the mandate to study the prevalence of vector species and transmission dynamics of malaria in the state, clinical drug trials, malaria disease burden estimation including malaria in pregnancy, malaria epidemiology and control, filariasis survey in Jharkhand state to prepare a filarial map and formulate the strategy for the control of filariasis, mapping of insecticide resistance of malaria vector in Jharkhand state and identification of malaria transmission risk factors in problematic districts of Jharkhand, establishment of larvivorous fish hatcheries of Gambusiaaffinis, Poecilliareticulata and local larvivorous fishes, to study the prevalence of G-6-PD deficiency and other genetic disorders in tribal population of the state, identification of foci of kala-azar and the reasons for its persistence in SanthalPargana (Sahibganj, Pakur, Dumka and Godda), to evaluate and develop effective interventions against vector borne diseases appropriate to the needs of local area and to provide technical support to the NVBDCP, such as in malaria investigations, training, IEC etc.

The FU operates from three places i.e. 1) IDVC, Field unit, Itki, Ranchi 2) Rajendra Institute of Medical science (RIMS), Ranchi (clinical drug trials unit) and 3) Model Rural Health Research Unit, at CHC Angara, Ranchi

Research Staff

Research Staff

  1. Piyoosh Kumar Singh, Scientist B & Officer In-Charge
  2. Manoj K Das, Ex. Scientist E & Consultant
  3. M Rajesh Kumar Rao, Technical Officer
  4. Vijay Om Gupta, Lab technician
  5. N K Shukla, Lab technician
  6. Dipak Kumar Mallick, Technician C
Ongoing Research Projects

Ongoing Research Projects

  1. Safety and Efficacy of 5-aminolevulinic acid hydrochloride (5-ALA-HCL) and Sodium Ferrous Citrate (SFC) in patients with uncomplicated Plasmodium falciparum malaria.(2019-2020)
  2. A Phase 2 interventional, multicenter, randomized open-label study to determine the effective and tolerable dose of KAF156 and Lumefentrine Solid Dispersion Formulation in combination, given once daily for 1, 2 and 3-days to adults and children with uncomplicated Plasmodium falciparum malaria(site initiation meeting and training and evaluation of Lab technician was completed) (2019-22)
  3. Bio-ecology of An. minimus and its distribution in Noamundi, West Sighbhum and other districts of Jharkhand state. (2019-2020)
  4. Development of rapid point of care immunological and molecular diagnostics for lymphatic filariasis (2018-2020)
  5. Biology and bionomics of. An. fluviatilis and An. minimus group and their role in malaria transmission in forest ecotype of West Singhbhum area, Jharkhand state (2019-2021)
  6. Study on the Epidemiology of Plasmodium knowlesi transmitted malaria in India.(2018-2022)
  7. Evaluation of one minute malaria Diagnosis malaris Device: Magneto Malaria Detection (MOD) (2019-2020)
  8. Malaria Evolution in South Asia: Epidemiology of Drug Resistance. (2019-22)
  9. A study of genomic diversity to develop SNP Barcode in Indian Plasmodium falciparum.
Recent Research Publications (last 5 years)

Recent Research Publications (last 5 years)

  1. Garcia-Senosiain A, Kana IH, Singh SK, Chourasia BK, Das MK, Dodoo D, Singh S, Adu B, Theisen M. Peripheral merozoite surface proteins are targets of naturally acquired immunity against malaria both in India and in Ghana. Infection and Immunity. 2020 Jan 21.
  2. Savargaonkar D, Das MK, Verma A, Mitra JK, Yadav CP, Srivastava B, Anvikar AR, Valecha N. Delayed haemolysis after treatment with intravenous artesunate in patients with severe malaria in India. Malaria Journal. 2020 Dec 1;19(1):39.
  3. Sandhu BK, Sakshi HS, Ahmed N, Rana R, Das MK, Singh S, Das S, Tiwari S, Kapoor N, Mishra N. Screening of Antimalarial Medicines Quality across Selected Sites in India.
  4. Anvikar AR, Kuepfer I, Mishra V, Bruce J, Arya T, Mishra DR, Mohanty S, Mohanty R, Srivastava B, Sharma S, Mishra N. Efficacy of two artemisinin-based combinations for the treatment of malaria in pregnancy in India: a randomized controlled trial. Malaria journal. 2018 Dec;17(1):246.
  5. Kana IH, Garcia-Senosiain A, Singh SK, Tiendrebeogo RW, Chourasia BK, Malhotra P, Sharma SK, Das MK, Singh S, Adu B, Theisen M. Cytophilic antibodies against key Plasmodium falciparum blood stage antigens contribute to protection against clinical malaria in a high transmission region of Eastern India. The Journal of infectious diseases. 2018 Aug 14;218(6):956-65.
  6. Ray HN, Doshi D, Rajan A, Singh AK, Singh SB, Das MK. Cardiovascular involvement in severe malaria: A prospective study in Ranchi, Jharkhand. Journal of vector borne diseases. 2017 Apr 1;54(2):177.
  7. Das MK, Prajapati BK, Tiendrebeogo RW, Ranjan K, Adu B, Srivastava A, Khera HK, Chauhan N, Tevatiya S, Kana IH, Sharma SK. Malaria epidemiology in an area of stable transmission in tribal population of Jharkhand, India. Malaria journal. 2017 Dec;16(1):181.
  8. Rao MR, Padhy RN, Das MK. Episodes of the epidemiological factors correlated with prevailing viral infections with dengue virus and molecular characterization of serotype-specific dengue virus circulation in eastern India. Infection, Genetics and Evolution. 2018 Mar 1;58:40-9.
  9. Pandey S, Das MK, Dhiman RC. Diversity of breeding habitats of anophelines (Diptera: Culicidae) in Ramgarh district, Jharkhand, India. Journal of vector borne diseases. 2016 Dec 1;53(4):327.
  10. Mishra N, Srivastava B, Bharti RS, Rana R, Kaitholia K, Anvikar AR, Das MK, Ghosh SK, Bhatt RM, Tyagi PK, Dev V. Monitoring the efficacy of antimalarial medicines in India via sentinel sites: outcomes and risk factors for treatment failure. Journal of vector borne diseases. 2016 Jun 1;53(2):168.
  11. Dykes CL, Das MK, Eapen A, Batra CP, Ghosh SK, Vijayan VA, Mishra S, Singh OP. Knockdown resistance (kdr) mutations in Indian Anopheles stephensi (Diptera: Culicidae) populations. Journal of medical entomology. 2016 Mar 1;53(2):315-20.
  12. Rao MR, Padhy RN, Das MK. Prevalence of dengue viral and malaria parasitic co-infections in an epidemic district, Angul of Odisha, India: An eco-epidemiological and cross-sectional study for the prospective aspects of public health. Journal of infection and public health. 2016 Jul 1;9(4):421-8.
  13. Rao K, Padhy RN, Das M. Surveillance on malaria and dengue vectors fauna across Angul district of Odisha, India: an approach to determine their diversity and abundance, correlation with the ecosystem. J Entomol Zool Stud. 2015;3:459-69.
  14. Pandey S, Das MK, Singh RK, Dhiman RC. Anopheline mosquitoes in District Ramgarh (Jharkhand), India. Journal of vector borne diseases. 2015 Sep 1;52(3):232.
  15. Dykes CL, Kushwah RB, Das MK, Sharma SN, Bhatt RM, Veer V, Agrawal OP, Adak T, Singh OP. Knockdown resistance (kdr) mutations in Indian Anopheles culicifacies populations. Parasites & vectors. 2015 Dec;8(1):333.
  16. Singh OP, Dykes CL, Sharma G, Das MK. L1014F-kdr Mutation in Indian Anopheles subpictus (Diptera: Culicidae) arising from two alternative transversions in the voltage-gated sodium channel and a single PIRA-PCR for their detection.Journal of medical entomology. 2015 Jan 1;52(1):24-7.
  17. Saxena R, Das MK, Nagpal BN, Srivastava A, Gupta SK, Kumar A, Tomar AS, Sinha AT, Vidyotma R, Jeyaseelan AT, Baraik VK. Identification of risk factors for malaria control by focused interventions in Ranchi district, Jharkhand, India. Journal of vector borne diseases. 2014 Dec 1;51(4):276.

Contact details

ICMR-National Institute of Malaria Research Field Unit
T. B. Sanitorium complex
Itki, Ranchi
Jharkhand-835301, India.
Phones: +91-6529-227190
Email: drpksingh45[at]gmail.com

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