National Institute of Malaria Research

 

+91-11-25307103 / 104            director@mrcindia.org

NIMR Field Unit: Guwahati (Assam)

Among net work of field stations under “Integrated Disease Vector Control Project”, this unit was initially established in Sonapur, the Dimoria block of Kamrup district of Assam in 1986 for persistent transmission of malaria and contributing most cases and deaths annually in the State. The main objectives were to field test newer interventions for containment of malaria transmission and subsequent transfer of technology to strengthen the national malaria control programme. It was in 2008 that this station was shifted to Guwahati city due to logistics requirements. Ever since inception of the station, number of technologies were evaluated to mention a few: (i) insecticide-treated mosquito nets/ long-lasting insecticidal nets for vector control, (ii) monitoring therapeutic efficacy of antimalarial medicines for treatment of Plasmodium falciparum malaria, (iii) evaluation of rapid test kits for diagnosis of malaria, (iv) promoting environment management methods for control of mosquito breeding, (iv) capacity building exercises for strengthening State healthcare services. Taken together all these newer interventions were incorporated in healthcare services resulting in substantial disease transmission reduction, and communities at stake today are more aware of the disease prevention and control. The future priorities include building cross-border initiative preventing entry and dissemination of multi-drug resistant malaria and monitoring insecticide resistance in disease mosquito vector species in northeast region of India.

Research Staff

Dr. Vas Dev DD, Scientist F, Officer-in-charge

Dr. Hardeo Prasad, Research Officer

Mr S. Phookan,  Assistant Research Officer

Mr. Tilak Baishya,  Technical Assistant

Mr. Mukesh Rahman,  Technical Assistant

Ms. Archana Gupta Lab Technician

Mr Prince Chetia Lab Technician

Ongoing Research Projects:

1. Monitoring therapeutic efficacy of antimalarial medicines in India (Project ID: NIMR/ECR/2015/320)  Co-Investigator

2. Malaria treatment practices with special emphasis on the private sector in India – Phase II Intramural Co-Investigator

3. Assessment of 24 hour Urinary Sodium Excretion levels in urban men and women in Andhra Pradesh and Assam for validation of consumption levels of Sodium assessed through 24 hour dietary recall method    Local Coordinator

4. Infectious reservoir of Plasmodium infections and monitoring antimalarial drug resistance in East Garo Hills district, Meghalaya and Udalguri district, Assam  Northeast  India)  Principal Investigator

5. Evaluation of the activities and performance of Accredited Social Health Activists (ASHA) with special reference to malaria control programme in Karbi angling hill district of Assam. Intramural Co-Investigator

6. Monitoring of Insecticide Resistance in malaria vectors in endemic states of India (Multi-centre study)  Principal Investigator

Recent Research Publications

Morgan, K., Linton, Y-M., Somboon, P., Saikia, P., Dev, V., Socheat, D. and Walton, C (2010). Inter-specific gene flow dynamics during the Pleistocene-dated speciation of forest-dependent mosquitoes in Southeast Asia. Molecular Ecology, 19: 2269 – 2285

Valecha, N., Phyo, A.P., Mayxay, M., Newton, P.N., Krudsood, S., Koemany, S., Khanthavong, M., Pongvongsa, T., Ruangveerayuth, R., Uthaisil, C., Ubben, D., Duparc, S., Bacchieri, A., Corsi, M., Rao, B.H.K., Bhattacharya, P.C., Dubhashi, N., Ghosh, S.K., Dev, V., Kumar, A. and Pukittayakamee, S (2010). An open-label, randomized study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falcipaum malaria in Asia. PLoS ONE, 5 (7), e11880.

Dev, V., Sangma, BM, Dash, AP (2010). Persistent transmission of malaria in Garo hills of Meghalaya bordering Bangladesh, north-east India. Malaria Journal, 9:263 (accessions >1250) (doi:10.1186/1475-2875-9-263).

Dev, V. (2010). Book Review, Malaria in South Asia: Eradication and Resurgence during the second half of the twentieth century (Eds., R. Akhtar, A. Dutt and V. Wadhwa, Sringer, Germany, pp. 241. Current Science, 99: 1122 – 1123.

Dev, V. (2010). Malaria recession and the way forward. Current Science, 99: 1507 – 1509.

Dev, V. (2010). Technical Report, “Strengthening the capacity of Bhutan malaria control programme in response to epidemics with particular emphasis on vector surveillance and cross-border activities. World Health Organization, Assignment Report TRL53651, 2010”.

Srivastava, A., B.N. Nagpal, R. Saxena and V. Dev (2010). RS and GIS in mapping the distribution of malaria vectors. In: “Application of GIS and RS technologies in Epidemiology and Control of Vector-borne Diseases” publication of the Epidemiology and Communicable Diseases division (ICMR), New Delhi, Chapter 2.3, pp 17-30.

Lumb, V., M., M.K. Das, N. Singh, V. Dev, Wajihullah and Y.D. Sharma (2011). Multiple origins of Plasmodium falciparum dihydropteroate synthetase mutant alleles associated with sulfadoxine resistance in India. Antimicrob Agents Chemother., 55: 2813-2817.

Prajapati, S.K., H. Joshi, V. Dev and V.K. Dua (2011). Molecular epidemiology of Plasmodium vivax anti-folate resistance in India. Malaria J. 10: 102.

Dev, V., S. Phookan, K. Padhan, G.G. Tewari and K. Khound (2011). Laboratory wash-resistance and field evaluation of deltamethrin incorporated long-lasting polyethylene netting (Netprotect®) against malaria transmission in Assam, north-east India. Acta Tropica 119: 172 – 177.

126 Dev, V. (2011). Technical Report, “Assessment of receptivity and vulnerability of development project sites to malaria in Bhutan. World Health Organization, Assignment Report TRL53651, 2011”.

127 Prajapati, S.K., H. Joshi, S. Shalini, M. Patarroyo, R. Suwanarusk, A. Kumar, S. Sharma, A. Eapen, V. Dev, R. Bhatt, N. Valecha, F. Nosten, M. Rizvi, and A. Dash (2011). Plasmodium vivax lineages: geographical distribution, tandem repeat polymorphism, and phylogenetic relationships. Malaria J, 10: 374

128 Lumb, V., R. Madan, M.K. Das, V. Rawat, V. Dev, W. Khan, H. Khan and Y.D. Sharma (2012). Differential genetic hitchhiking around mutant pfcrt alleles in Indian Plasmodium falciparum population. J. Antimicrob Chemother., 67: 600 – 608.

Yangzom, T., C.S. Gueye, R. Namgay, GNL Galappaththy, K. Thimasarn, R. Gosling, S. Murugasampillay and V. Dev (2012). Malaria control in Bhutan: case study of a country embarking on elimination. Malaria J, 11: 9

Jhajharia, D., S. Chattopadhyay, R.R. Choudhary, V. Dev, V.P. Singh and S. Lal (2013). Influence of climate on incidences of malaria in the Thar Desert, northwest India. Int. J. Climatol 33: 312–325.

Gargano, N., D. Ubben, S. Tommasini, A. Bacchieri, M. Corsi, P.C. Bhattacharyya, B.H.K. Rao, N. Dubashi, V. Dev, S.K. Ghosh, A. Kumar, B. Srivastava, N. Valecha (2012). Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India.  Malaria J, 11: 233.

Dev, V. and Vinod P. Sharma (2013). The Dominant Mosquito Vectors of Human Malaria in India, Anopheles mosquitoes - New insights into malaria vectors, Prof. Sylvie Manguin (Ed.), ISBN: 978-953-51-1188-7, InTech, DOI: 10.5772/55215, pp.239-271. Available from: http://www.intechopen.com/books/anopheles-mosquitoes-new-insights-into-malaria-vectors/the-dominant-mosquito-vectors-of-human-malaria-in-india.

Srivastava, D.K., Dev, V., S. Bhattacharya (2013). Predatory potential of indigenous and exotic larvivorous fish for control of mosquito breeding. Journal of Applied Bioscience, 39 (2): 127-130.

Dev V, Khound K, Tewari GG (2014). Dengue vectors in urban and suburban Assam, India: entomological observations. WHO South-East Asia J Public Health; 3(1): 51–59.

Mishra N, Kaitholia K, Srivastava B, Shah NK, Narayan JP, Dev V, Phookan S, Anvikar AR, Rama R, Bharti RS, Sonal GS, Dharival AC, Valecha N (2014). Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India. Malaria J. 13: 284. doi:10.1186/1475-2875-13-284.

Sexena R, BN Nagpal, VP Singh, A Srivastava, V Dev, MC Sharma, HP Gupta, AS Tomar, S Sharma, SK Gupta (2014). Impact of deforestation on known malaria vectors in Sonitpur district of Assam, India. J Vector Borne Dis 51: 211-215.

Dev V (2014). Long-lasting insecticidal nets, an appropriate technology for malaria vector control in tribal India. Tribal Health Bulletin 21(2): 11-22.

Sharma VP, Dev V (2015). Biology and Control of Anopheles culicifacies Giles 1901. Indian J Med Res 141: 525-536.

Sharma VP, Dev V, Phookan S (2015) Neglected Plasmodium vivax malaria in Northeastern States of India. Indian J Med Res 141: 546-555.

Dev V, Mahanta N, Baruah BK (2015). Dengue, an emerging infection in Assam, Northeast India. Tropical Biomedicine (Accepted for publication).

Dev V, Adak T, Singh OP, Nanda N and Baidya BK (2014). Malaria transmission in Tripura: disease distribution and determinants. Indian J Med Res. (Accepted for publication).

Mishra N, Prajapati S, Kaitholia K, Bharti R, Srivastava B, Phookan S, Anvikar A, Dev V, Sonal G, Dhariwal A, White N, and Valecha N (2015). Surveillance for artemisinin resistance in Plasmodium falciparum in India using the kelch13 molecular marker. J. Antimicrob Chemother 59: 2548–53.

Kushwah RBS, Mallick PK, Ravikumar H, Dev V, Kapoor N, Adak T,  Singh OP (2015). Status of DDT and pyrethroid resistance in Indian Aedes albopictus and absence of knockdown resistance (kdr) mutation. J Vector Borne Dis 52: 95 – 98.

Dev, V. (2014). Plasmodium falciparum – A persistent threat and continuing challenge for containment. Guest Column in Plasmodium, a newsletter of the National Institute of Malaria Research, New Delhi, Issue of January – December, 2014.

Dev V, VP Sharma, K Barman (2015). Mosquito-borne diseases in Assam, north-east India: current status and key challenges. WHO South-East Asia J Public Health; 4: 20-29.

Dev V, Barman K,  Khound K (2015). A cross-sectional study for assessing residual bio-efficacy and durability of field distributed long-lasting insecticidal nets in malaria endemic ethnic communities of Assam, Northeast India. J Infect Pub Hlth (Accepted for publication).

Dutta P, Khan SA, Chetry S, Dev V, Sharma, K. C, Mahnata J (2015).  First evidence of dengue virus infection in wild caught mosquitoes during an outbreak in Assam, Northeast India. J Vector Borne Dis (Accepted for publication)

 

Contact details

National Institute of Malaria Research

Chachal, VIP Road, Guwahati - 781 022 , Assam (INDIA)

Cell: +91 94353 45154

Email: mrcassam[at]hotmail.com

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